A preliminary study on the antibacterial activity of Quercus brantii against bacterial pathogens, particularly enteric pathogens

Abstract

The antibacterial activity of Q. brantii fruits ethanolic and methanolic extracts were examined using agar disc diffusion method against eight bacteria (Salmonella typhi, Proteus mirabilis, Shigella dysenteriae, Escherichia coli, Klebsiella pneumoniae, Brucella melitensis, Bordetella bronchiseptica, Pseudomonas aeruginosa). These extracts had inhibitory effect at various concentrations (0.5, 0.1, 0.2, 0.3 and 0.4 g mL-1) against tested bacteria. The ethanolic extract had the highest activity (30 mm) against Br. melitensis and B. bronchiseptica while the lowest activity (7 mm) was demonstrated by the methanolic extract on E. coli. Studies on the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the methanolic extract on tested microorganisms showed that the highest MIC (20 mg mL-1) and MBC (32 mg mL-1) were demonstrated against Sh. dysenteriae, B. bronchiseptica and P. mirabilis had the highest MIC and MBC values (32 mg mL-1) for the ethanolic extract. © 2009 Asian Network for Scientific Information.