Selection of potential therapeutic bacteriophages that lyse a CTX-M-15 extended spectrum β-lactamase producing Salmonella enterica serovar typhi strain from the democratic republic of the Congo

Elene Kakabadze; Khatuna Makalatia; Nino Grdzelishvili; Nata Bakuradze; Marina Goderdzishvili; Ia Kusradze; Marie France Phoba; Octavie Lunguya; Cédric Lood; Rob Lavigne; Jan Jacobs; Stijn Deborggraeve; Tessa De Block; Sandra Van Puyvelde; David Lee; Aidan Coffey; Anahit Sedrakyan; Patrick Soentjens; Daniel De Vos; Jean Paul Pirnay; Nina Chanishvili

Journal ArticleOPEN ACCESS

Selection of potential therapeutic bacteriophages that lyse a CTX-M-15 extended spectrum β-lactamase producing Salmonella enterica serovar typhi strain from the democratic republic of the Congo

Viruses (2018) 10(4)

DOI: 10.3390/v10040172

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Abstract

Recently, a Salmonella Typhi isolate producing CTX-M-15 extended spectrum β-lactamase (ESBL) and with decreased ciprofloxacin susceptibility was isolated in the Democratic Republic of the Congo. We have selected bacteriophages that show strong lytic activity against this isolate and have potential for phage-based treatment of S. Typhi, and Salmonella in general.

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Kakabadze, E., Makalatia, K., Grdzelishvili, N., Bakuradze, N., Goderdzishvili, M., Kusradze, I., … Chanishvili, N. (2018). Selection of potential therapeutic bacteriophages that lyse a CTX-M-15 extended spectrum β-lactamase producing Salmonella enterica serovar typhi strain from the democratic republic of the Congo. Viruses, 10(4). https://doi.org/10.3390/v10040172

Selection of potential therapeutic bacteriophages that lyse a CTX-M-15 extended spectrum β-lactamase producing Salmonella enterica serovar typhi strain from the democratic republic of the Congo

Abstract

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