Abstract
The asymmetric-transfer hydrogenation of 2-tosyloxy-1-(2-thiophenyl) ethanone and further elaboration of the cyclic carbamate derived from ?-aminoalcohol to provide a facile synthesis of (S)-duloxetine, a potent dual inhibitor of serotonin and norepinephrine reuptake, is described. © ARKAT USA, Inc.
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APA
Kwak, S. H., Seo, J. M., & Leea, K. I. (2010). A facile asymmetric synthesis of (S)-duloxetine. Arkivoc, 2010(10), 55–61. https://doi.org/10.3998/ark.5550190.0011.a05
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