Phosphotungstic acid: An efficient, cost-effective and recyclable catalyst for the synthesis of polysubstituted quinolines

Abstract

Phosphotungstic acid (H3PW12O40) was used as an efficient and recyclable catalyst for the synthesis of polysubstituted quinolines through the Friedländer condensation of 2-aminoarylketone with carbonyl compounds, which was achieved by conventional heating under solvent-free conditions.