Abstract
Three new pentaene macrolides having a 28-membered ring, designated takanawaenes A, B and C, were isolated from the fermentation broth of Streptomyces sp. K99-5278 by solvent extraction, silica-gel column chromatography and HPLC. Takanawaenes showed antifungal activity against Aspergillus niger, Mucor racemosus, Candida albicans and Saccharomyces cerevisiae.
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CITATION STYLE
Kim, Y. P., Tomoda, H., Iizima, K., Fukuda, T., Matsumoto, A., Takahashi, Y., & Omura, S. (2003). Takanawaenes, novel antifungal antibiotics produced by Streptomyces sp. K99-5278. I. Taxonomy, fermentation, isolation and biological properties. Journal of Antibiotics, 56(5), 448–453. https://doi.org/10.7164/antibiotics.56.448
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