Dendritic maleimide functionalization of core-shell (γ-Fe2O3/polymer) nanoparticles for efficient bio-immobilization

Abstract

A new route for the preparation of stable and water-dispersible core-shell γ-Fe2O3/polymer MNPs has been developed in order to ensure a selective and covalent immobilization of biomolecules using maleimide-thiol coupling chemistry. A high maleimide functionalization was achieved by the grafting of dendritic coupling agent via a convergent approach.