Multinucleation of the sodC-deficient Dictyostelium discoideum

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Abstract

The cellular slime mold Dictyostelium discoideum expresses three genes (sodA, sodB and sodC) encoding the extracellular Cu/Zn superoxide dismutases. Following H2O2 treatment, the expression of sodA and sodB increased while that of sodC decreased. The sodC null strain formed multinucleate cells in a shaking culture. These results suggest that sodC plays a unique role in Dictyostelium discoideum.

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Tsuji, A., Akaza, Y., Nakamura, S., Kodaira, K. I., & Yasukawa, H. (2003). Multinucleation of the sodC-deficient Dictyostelium discoideum. Biological and Pharmaceutical Bulletin, 26(8), 1174–1177. https://doi.org/10.1248/bpb.26.1174

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