In vitro efficacy of the combination of ciprofloxacin and cefotaxime against Vibrio vulnificus

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Abstract

We performed time-kill studies of antimicrobial combinations that included minocycline, cefotaxime, and ciprofloxacin with Vibrio vulnificus ATCC 27562. Cefotaxime-plus-ciprofloxacin combinations acted synergistically against V. vulnificus in vitro, and this combination regimen can be a good choice as the empirical treatment for suspected necrotizing fasciitis due to V. vulnificus. Copyright © 2005, American Society for Microbiology. All Rights Reserved.

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Kim, D. M., Lym, Y., Jang, S. J., Han, H., Kim, Y. G., Chung, C. H., & Hong, S. P. (2005). In vitro efficacy of the combination of ciprofloxacin and cefotaxime against Vibrio vulnificus. Antimicrobial Agents and Chemotherapy, 49(8), 3489–3491. https://doi.org/10.1128/AAC.49.8.3489-3491.2005

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