Abstract
Wire to wire: The hybrid Sup351-61-E2GFP-MPH, which consists of the pH-sensitive green fluorescent protein E2GFP, the enzyme methyl parathion hydrolase (MPH), and the yeast prion protein Sup35 1-61 was obtained by gene fusion. A self-assembled nanowire was formed through aggregation ofthe Sup351-61 sub-unit (see picture). The wire acts as a biosensor that can detect methyl para-thion with a sensitivity 10000 times greater than free E2GFP-MPH. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
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CITATION STYLE
Leng, Y., Wei, H. P., Zhang, Z. P., Zhou, Y. F., Deng, J. Y., Cui, Z. Q., … Zhang, X. E. (2010). Integration of a fluorescent molecular biosensor into self-assembled protein nanowires: A large sensitivity enhancement. Angewandte Chemie - International Edition, 49(40), 7243–7246. https://doi.org/10.1002/anie.201002452
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