Copper-mediated conversion of alkynes into nitriles via iodotriazoles

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Abstract

We disclose our studies on a copper-mediated reaction of alkynes with trimethylsilyl azide to afford nitriles, and proposed a reaction mechanism, which involves an iodoalkyne and an iodotriazole as intermediates.

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Kori, R., Murakami, K., Nishiyama, Y., Toma, T., & Yokoshima, S. (2021). Copper-mediated conversion of alkynes into nitriles via iodotriazoles. Chemical and Pharmaceutical Bulletin, 69(3), 278–280. https://doi.org/10.1248/cpb.c20-00787

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