Addiction to Prednisone

Abstract

It is well known that cortisone and its analogues when taken in high dosage may cause acute mental disturbance such as delirium (Engel and Romans, 1959), in about 50% of cases a euphoric rise of mood being the main clinical feature (Michael and Gibbons, 1963). It follows that when steroids are used therapeutically subjective improvement may not only be related to actual suppression of the underlying organic disease. © 1973, British Medical Journal Publishing Group. All rights reserved.