Mekonyum Aspirasyon Sendromu

Abstract

Meconium-stained amniotic fluid occurs in approximately 13% of normal pregnancies and 5% of these infants develop meconium aspiration syndrome. Meconium aspiration syndrome is mostly a problem of term and postterm infants. There may be mild tachypnea or dispnea, respiratory insufficiency and persistant pulmonary hypertension in meconium aspiration syndrome. Meconium aspiration syndrome has a complex pathophysiology. Babies with meconium aspiration syndrome have both acute effects and long term morbidities such as bronchial reactivity and wheezing. Although there is improvement in pathophysiology and treatment modalities, it is still difficult to treat meconium aspiration syndrome. In this paper, management of newborns with meconium stained amniotic fluid and meconium aspiration syndrome in antenatal, natal and postnatal period are reviewed.