Synthesis, biological evaluation of 1,3,4-oxadiazole, triazole and uracil derivatives from poly (ethylene terephthalate) waste

Abstract

POLY(ethylene terephthalate) (PET) was hydrolyzed in aqueous NaOH using solar energy. PET is used as versatile reagent for the synthesis of a variety of heterocyclic compounds. Uracil (6a, b), 1,3,4-oxadiazole (9, 12a, b), 1,3,4-triazole (10, 14), thiadiazole (11a, b and 15) derivatives were synthesized from PET. The antimicrobial and antioxidant activities of the synthesized compounds were evaluated and showed significant activities.