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The asymmetric A3(aldehyde–alkyne–amine) coupling: Highly enantioselective access to propargylamines

Molecules
DOI: 10.3390/molecules24071216
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Abstract

The recent developments in asymmetric A3 (aldehyde–alkyne–amine) coupling has been summarized in this review. Several interesting modifications of the ligands enabled the highly enantioselective synthesis of chiral propargylamines, which are further used in the construction of nitrogen-containing chiral building blocks.

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Mo, J. N., Su, J., & Zhao, J. (2019, March 28). The asymmetric A3(aldehyde–alkyne–amine) coupling: Highly enantioselective access to propargylamines. Molecules. MDPI AG. https://doi.org/10.3390/molecules24071216

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