Dangerous liaisons on neurons

  • Schiavo G
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Abstract

Crystal structures show that botulinum toxins bind simultaneously to two sites on neurons. This dual interaction allows them to use a Trojan-horse strategy to enter nerve terminals, with deadly effect.

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Schiavo, G. (2006). Dangerous liaisons on neurons. Nature, 444(7122), 1019–1020. https://doi.org/10.1038/nature05410

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