Microparticles Induce Cell Cycle Arrest Through Redox‐Sensitive Processes in Endothelial Cells: Implications in Vascular Senescence

Dylan Burger; Dylan G. Kwart; Augusto C. Montezano; Naomi C. Read; Christopher R.J. Kennedy; Charlie S. Thompson; Rhian M. Touyz

Journal ArticleOPEN ACCESS

Microparticles Induce Cell Cycle Arrest Through Redox‐Sensitive Processes in Endothelial Cells: Implications in Vascular Senescence

Burger D
Kwart D
Montezano A
et al.

Journal of the American Heart Association (2012) 1(3)

DOI: 10.1161/jaha.112.001842

N/ACitations

71Readers

Abstract

Chronic disease accelerates endothelial dysfunction in aging, a process associated with cell senescence. However, the mechanisms underlying this process are unclear. We examined whether endothelial cell (EC)-derived microparticles (MPs) facilitate EC senescence and questioned the role of reactive oxygen species in this process.

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Burger, D., Kwart, D. G., Montezano, A. C., Read, N. C., Kennedy, C. R. J., Thompson, C. S., & Touyz, R. M. (2012). Microparticles Induce Cell Cycle Arrest Through Redox‐Sensitive Processes in Endothelial Cells: Implications in Vascular Senescence. Journal of the American Heart Association, 1(3). https://doi.org/10.1161/jaha.112.001842

Microparticles Induce Cell Cycle Arrest Through Redox‐Sensitive Processes in Endothelial Cells: Implications in Vascular Senescence

Abstract

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