We report the first case of cryptococcosis due to Cryptococcus decagattii in an immunocompetent pediatric patient from an indigenous community in Argentina with a successful outcome. Two isolates (blood, cerebrospinal fluid) were genotyped by restriction fragment length polymorphism of the orotidine monophosphate pyrophosphorylase (URA5) gene as VGIV and identified by multi-locus sequence typing as C. decagattii. Matrix-assisted laser desorption/ionization time of flight mass spectrometry identification indicated genotype VGIII. The minimum inhibitory concentration of amphotericin B, fluconazole, itraconazole, and voriconazole was determined (cerebrospinal fluid: 0.25, 16, 0.12, and 0.12, blood: 0.25, 4, 0.12, and 0.06, respectively, all in mg/L).
CITATION STYLE
Berejnoi, A., Taverna, C. G., Mazza, M., Vivot, M., Isla, G., Córdoba, S., & Davel, G. (2019). First case report of cryptococcosis due to Cryptococcus decagattii in a pediatric patient in Argentina. Revista Da Sociedade Brasileira de Medicina Tropical, 52. https://doi.org/10.1590/0037-8682-0419-2018
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