Long non-coding RNAs (lncRNAs), transcripts as longer than 200 nt in length with a great number of varieties in human genomics, play important roles in the regulation of genetics and epigenetics including gene transcription and post-transcription. Increasing evidence have demonstrated the upregulation of lncRNAs in tumorigenesis and metastasis of esophageal cancer (EC), a type of malignant tumors particularly in Asia. In this review, we briefly discuss the profiles and functions of lncRNAs involved in the progression of EC, which may provide a new approach to improve EC diagnosis and treatment.
CITATION STYLE
Tang, W. W., Wu, Q., Li, S. Q., Tong, Y. S., Liu, Z. H., Yang, T. X., … Cao, X. F. (2015, November 3). Implication of lncRNAs in pathogenesis of esophageal cancer. OncoTargets and Therapy. Dove Medical Press Ltd. https://doi.org/10.2147/OTT.S87856
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