Deficiency in superoxide dismutases shortens life span of yeast cells

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Abstract

Deficiencies in superoxide dismutases (Cu,Zn-SOD or Mn-SOD) strongly shorten the life span of yeast cells. The effects of these deficiencies are additive. In contrast, deficiencies in catalases do not influence life span. Our results confirm that free radical processes may be involved in aging.

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Wawryn, J., Krzepiłko, A., Myszka, A., & Biliński, T. (1999). Deficiency in superoxide dismutases shortens life span of yeast cells. Acta Biochimica Polonica, 46(2), 249–253. https://doi.org/10.18388/abp.1999_4158

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