Amyloid-β ‘seeds’ in old vials of growth hormone

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Abstract

Some samples of human growth hormone used as therapy until the mid-1980s contain amyloid-β peptide and cause genetically modified mice to develop amyloid-β deposits in the brain.

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Huynh, T. P. V., & Holtzman, D. M. (2018, December 20). Amyloid-β ‘seeds’ in old vials of growth hormone. Nature. Nature Publishing Group. https://doi.org/10.1038/d41586-018-07604-6

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