Saponin and Sapogenol. XLVII. On the Constituents of the Roots of Glycyrrhiza uralensis fischer from Northeastern China. (1). Licorice-Saponins A3, B2, and C2

Abstract

From the air-dried root of Glycyrrhiza uralensis, collected in the northeastern part of China, ten new oleanane-type triterpene oligoglycosides were isolated together with glycyrrhizin (1) and several known flavonoids. Among the newly isolated triterpene oligoglycosides, the chemical structures of licorice-saponin A3 (2), licorice-saponin B2 (3), and licorice-saponin C2 (4) have been determined, on the basis of chemical and physicochemical evidence, to be expressed as 11-deoxo-glycyrrhizin, acid, respectively. During the course of these studies, facile conversions from glycyrrhizin (1) to licorice-saponins A3 (2), B2 (3), and C2 (4) have been accomplished. © 1993, The Pharmaceutical Society of Japan. All rights reserved.