Electrodeposition assisted dynamic assemblies of chitosan/alginate composite multi-membrane

Abstract

Electrodeposition of natural polymer as an effective approach to improve bioactivity of the conductive substrate has receives much attentions in medical and other applications. In this work, we developed a novel chitosan/alginate (CS/ALG) multi-membrane on titanium plate via the electrodeposition assisted dynamic assembly approach. Specifically, the electrical signal induced CS coating can serve as a versatile platform for layer by layer assemblies of ALG into the multi-membrane through strong electrostatic interaction. The prepared multi-membranes exhibit great swelling performance and excellent mechanical properties at dried states, with the tensile stress and strain values reaching to 58.2 MPa and 4.25 % for the 10 layers sample. In summary, we believe such green, low cost and rapid fabrication approach and mild processing environment would spur great potential for construction of multi-functional coating and smart drug elution system on the conductive implants.