Clinical outcome and prognostic factors for nasopharyngeal carcinoma: A single institution study in Iran

Abstract

Background: Evidence about survival of the patients with nasopharyngeal cancer is scant in our region and the aim of the current study was to determine clinico-pathological factors influencing outcome of these patients. Methods: We reviewed all patients with a new diagnosis of nasopharyngeal carcinoma admitted between 2008 and 2014 to Jorjani cancer center, Tehran, Iran. Overall survival (OS) of the patients and their relation with demographic and clinico-pathological factors were analyzed. Results: Of 88 included patients, 56 were male and 32 were female with mean age of 46 years. With a median follow-up period of 31 months (range: 3 to 86 months), the overall survival of the whole patients and those without distant metastasis were 64% and 67% respectively. Tumor stage and presence or absence of distant metastasis at presentation were the only parameters that significantly influenced the patients’ OS. Conclusions: Our study provides some evidence on the outcome of Iranian patients with nasopharyngeal cancer and factors influencing it.