A review on Nifedipine co-administered with Metoprolol succinate for the treatment of hypertension

Abstract

Hypertension and Angina pectoris area major public health problem in the developed Countries recently. Hypertension and Angina Pectoris are frequently treated with antihypertensive drugs like calcium-channel blockers, angiotensin-converting enzyme inhibitors, and angiotensin II (AT1) receptor blockers, and statins. Nifedipine is calcium-channel blockers and widely used in treatment of Angina pectoris condition. Metoprolol Succinate is Beta-adrenoreceptor blocker and widely used in treatment of hypertension condition. Combination of Nifedipine and Metoprolol Succinate is used in the treatment of cardiovascular diseases like hypertension and Angina Pectoris. So this combination therapy gives antihypertensive and Angina Pectoris effects in the treatment of cardiac diseases.