Development of an operator independent ultrasound therapeutic device for stroke treatment

Abstract

Ischemic stroke is one of the leading causes of mortality and morbidity worldwide. Low intensity transcranially applied ultrasound has been shown to augment cerebral arterial recanalization when administered in conjunction with tPA. However, ultrasound usually requires an experienced operator for proper alignment and operation. We have developed an operator independent ('hands free') device that can deliver ultrasound therapy to a larger patient population by obviating the need for ultrasound specialists in emergency situations. Design goals thus included simple operation and high likelihood of successful insonation of blocked arteries. Ultrasound dosimetry and controlled insonation were also important design factors. © 2012 IEEE.