Formulation & Development of Anti-Obesity Liquid Formulation Containing Garcinia Cambogia Extract, L-Carnitine & Chromium Picolinate

Abstract

The aim of the current investigation is to develop antiobesity liquid formulation of Garcinia cambogia extract, LCarnitine and Chromium Picolinate, which gives good microbial stability and pharmacological activity. The formulation was prepared by using coconut water as base and flavour in different combinations. The prepared formulation was evaluated for general description, microbiological and drug content. The formulation showed acceptable physical, microbiological properties and complied with drug content limits. The results of assay of Garcinia cambogia (HCA content) was 108.23% and 108.16%, before and after stability study, by HPLC. L-Carnitine content in formulation was 106.15% and 105.58%, before and after stability study, by HPLC. Chromium picolinate content was 99.2% and 97.8%, before and after stability study, by AAS. From the results it was concluded that the formulation was relative stable. © 2011 IGJPS. All rights reserved.