Selection of breeding stock in pigs favours 6PGD heterozygotes

Abstract

Associations between genetic variation at four enzyme polymorphisms and growth rate, feed conversion and economic index were studied in commercial lines of pigs. These lines were also tested for the fit of observed genotypic frequencies to expected genotypic frequencies at the four polymorphic loci. Genotypic distributions fit Hardy-Weinberg expectations in four pure-breeding lines but crosses among lines produced excesses in heterozygosity at the locus coding for 6-phos- phogluconate dehydrogenase (6PGD) due to differences in allelic frequencies among lines. Selection of breeding individuals further enhanced the heterozygosity at 6PGD to 73-93 per cent but it had no impact on a linked locus that was sometimes in linkage disequilibrium with 6PGD. The relationship between feed conversion and individual heterozygosity was examined in one population sample; feed conversion increased with individual heterozygosity. © The Genetical Society of Great Britain.