Arrhythmic Gut Microbiome Signatures Predict Risk of Type 2 Diabetes

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Abstract

Reitmeier et al. show that specific gut microbes exhibit rhythmic oscillations in relative abundance and identified taxa with disrupted rhythmicity in individuals with type 2 diabetes (T2D). This arrhythmic signature contributed to the classification and prediction of T2D, suggesting functional links between circadian rhythmicity and the microbiome in metabolic diseases.

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Reitmeier, S., Kiessling, S., Clavel, T., List, M., Almeida, E. L., Ghosh, T. S., … Haller, D. (2020). Arrhythmic Gut Microbiome Signatures Predict Risk of Type 2 Diabetes. Cell Host and Microbe, 28(2), 258-272.e6. https://doi.org/10.1016/j.chom.2020.06.004

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