Lambert-eaton myasthenic syndrome and paraneoplastic cerebellar degeneration associated with merkel cell carcinoma with unknown primary: A case report

Abstract

Merkel cell carcinoma (MCC) is a rare aggressive skin cancer, the incidence of which is increasing rapidly (1). Various paraneoplastic syndromes have been associated with MCC, due to its neuroendocrine nature, and these could be the first manifestations of cancer (2–7). We report here a case of a patient whose diagnosis of MCC with unknown primary was made following the identification of 2 uncommon neurological disorders. This case report highlights the complexity of paraneoplastic syndrome associated with MCC and the importance of a multidisciplinary approach.