Evaluation of 5 commercially available Zika virus immunoassays

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Abstract

Because of the global spread of Zika virus, accurate and high-throughput diagnostic immunoassays are needed. We compared the sensitivity and specificity of 5 commercially available Zika virus serologic assays to the recommended protocol of Zika virus IgM-capture ELISA and plaque-reduction neutralization tests. Most commercial immunoassays showed low sensitivity, which can be increased.

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Safronetz, D., Sloan, A., Stein, D. R., Mendoza, E., Barairo, N., Ranadheera, C., … Drebot, M. (2017). Evaluation of 5 commercially available Zika virus immunoassays. Emerging Infectious Diseases, 23(9), 1577–1580. https://doi.org/10.3201/eid2309.162043

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