The Efficacy of Autologous Nanofat Injection in the Treatment of Infraorbital Dark Colouration

Abstract

Background: Periorbital hyperpigmentation is a common worldwide problem, which makes a person appear tired, sad, and aged. A number of factors can cause dark circles around the eyes including excessive pigmentation, thin and translucent lower eyelid skin overlying the orbicularis oculi muscle, and shadowing due to skin laxity and tear trough. Although a number of treatment options are available, autologous fat transplantation is an effective method for the treatment of lower lid dark circles, but irregularities caused by leaving visible lumps of the fat can occur. Mechanical emulsification of harvested fat achieves much more finer fat particles than micro-fat called nano-fat which acts primarily by the plenty the active transplanted stem cells the purpose of this study is to evaluate the effectiveness of the nanofat grafting technique in correcting infraorbital dark circles.