Research on Extraction Process of Gallic Acid from Penthorum chinense Pursh by Aqueous Ethanol

Abstract

Penthorum chinense Pursh is rich in gallic acid, which has antioxidant, anti-inflammatory, anti-fungal and antitumor activities. In order to optimize their extraction conditions, various extrac-tion parameters were chosen to identify their effects on gallic acid extraction. With extraction amount of gallic acid as index, based on single factor analysis, influence of solid/liquid ratio, ethanol concentration, fetch time and extraction temperature on extraction technology were in-vestigated by orthogonal test. The optimization conditions for gallic acid extraction were deter-mined as follows: ethanol concentration 60%, extraction time 2.5 h, temperature 90˚C and sol-id/liquid ratio 1:30. The corresponding gallic acid content was 4.85%. This optimized extraction process was stable and feasible.