New sterols and triterpenoids from four edible mushrooms

Abstract

Four edible mushrooms, Panellus serotinus, Lepista nuda, Tricholoma matsutake and Naematoloma sublateritium, have been investigated chemically. Two new sterols, 50α,90α-epidioxy-(22E)-ergosta-7,22-diene-3β,6α-diol (1) and 5α9α-epidioxy-(22E)-ergosta-7,22-diene-3β,6β-diol (2), have been isolated from Panellus serotinus. Compound 2 was also isolated from Lepista nuda. A new sterol, 3β,5α9α,14β-tetrahydroxy-(22E)-ergosta-7,22-dien-6-one (3), and compound 2 have been isolated from Tricholoma matsutake. Three new triterpenoids, sublateriols A-C (4-6), have been isolated from Naematoloma sublateritium. The structures of the new compounds were elucidated on the basis of their spectral data.