Risk factors and survival in patients with COVID-19 in northeastern Brazil

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Abstract

Background Knowledge about the epidemiology and risk factors surrounding COVID-19 contributes to developing better health strategies to combat the disease. Objective This study aimed to establish a survival analysis and identify the risk factors for patients with COVID-19 in an upper middle-income city in Brazil. Methods A retrospective cohort study was conducted with 280 hospitalized patients with COVID-19. The eCOVID platform provided data to monitor COVID-19 cases and help the communication between professionals. Results Age ≥ 65 years was associated with decreased survival (54.8%), and females had a lower survival rate than males (p = 0.01). Regarding risk factors, urea concentration (p<0.001), hospital length of stay (p = 0.002), oxygen concentration (p = 0.005), and age (p = 0.02) were associated with death. Conclusion Age, hospital length of stay, high blood urea concentration, and low oxygen concentration were associated with death by COVID-19 in the studied population. These findings corroborate with studies conducted in research centers worldwide.

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Fernandes, A. T., Rodrigues, E. K., Araújo, E. R., Formiga, M. F., Sá Horan, P. K., de Sousa Ferreira, A. B. N., … Barbosa, P. S. (2022). Risk factors and survival in patients with COVID-19 in northeastern Brazil. PLoS ONE, 17(11 November). https://doi.org/10.1371/journal.pone.0278213

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