Abstract
Saxitoxin (STX), a neurotoxin isolated from Alaskan butter clam, Saxidomus giganteus, inhibits voltage-gated sodium channels by binding to the pore-forming p-loop region. Here we describe stereospecific syntheses of STX and its natural derivatives, (+)-decarbamoylsaxitoxin (dcSTX) and (+)-gonyautoxin3 (GTX3). © 2012 IUPAC.
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APA
Iwamoto, O., Akimoto, T., & Nagasawa, K. (2012). Synthesis of saxitoxins. Pure and Applied Chemistry, 84(6), 1445–1453. https://doi.org/10.1351/PAC-CON-11-09-10
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