Therapy for Parkinson's Disease: What is in the Pipeline?

Abstract

Despite advances in the treatment of Parkinson's disease there are still many unmet needs, including neuroprotection, treatment of motor complications, treatment of dyskinesia, treatment of psychosis, and treatment of nondopaminergic symptoms. In this review, I highlight the obstacles to develop a neuroprotective drug and some of the treatment strategies recently approved or still in clinical trials designed to meet these unmet needs. © 2013 The American Society for Experimental NeuroTherapeutics, Inc.