Absolute configuration of beer's bitter compounds

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Abstract

During the beer brewing process, bitter tasting cis and trans iso-α-acids are generated from the precursor α-acids found in hops. The absolute configurations of the α-acid (-)-humulone and several of its derivatives have now been elucidated by X-ray crystallography, thus resolving decades of confusion over the humulone isomerization mechanism. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Urban, J., Dahlberg, C. J., Carroll, B. J., & Kaminsky, W. (2013). Absolute configuration of beer’s bitter compounds. Angewandte Chemie - International Edition, 52(5), 1553–1555. https://doi.org/10.1002/anie.201208450

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