Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome

Abstract

Metabolic syndrome is associated with increased propensity for diabetes and cardiovascular disease. Lowgrade inflammation is characteristic of metabolic syndrome. C-reactive protein, the best characterized biomarker of inflammation, is also an independent predictor of future cardiovascular events. This review outlines the role of highsensitivityC-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome by inducing endothelial cell dysfunction and activating monocytes. © The Author(s) 2010.