A New Synthesis of (±)-Lysergic Acid

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Abstract

A new and simple synthesis of (±)-lysergic acid from the aldehyde (5) is described involving aldol condensation with 3 in the presence of LDA as a key reaction. © 1986, The Pharmaceutical Society of Japan. All rights reserved.

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Kurihara, T., Terada, T., & Yoneda, R. (1986). A New Synthesis of (±)-Lysergic Acid. Chemical and Pharmaceutical Bulletin, 34(1), 442–443. https://doi.org/10.1248/cpb.34.442

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