Synthesis of novel symmetrical and unsymmetrical bis-spiro[indole- indazolyl-thiazolidine]-2,4'-diones

Abstract

A facile synthesis of novel symmetrical and unsymmetrical bis-[spiro(indole-indazolyl- thiazolidine)-2,4'-diones] 5a-f has been achieved via hitherto unknown bis-Schiff bases 3a-f, which in turn have been prepared from the earlier reported (1i7-indol-2,3-dione)-1,1'-(1,6- hexanediyl)bis 1a-c and 5-substituted-1-[6-(2,3-dioxoindolyl)hexyl]-1i7-indol-2,3-diones 1d-f. © ARKAT USA, Inc.