Ferritin and FerriScan in HCT recipients

Abstract

In this issue of Blood, Trottier et al. demonstrate that the outcome of allogeneic stem cell transplantation (HCT) was not significantly impacted by iron overload, as defined by liver magnetic resonance imaging (R2-MRI). This study implies that treatment decisions for iron overload should not be based on ferritin alone and that assessment of the liver iron content (LIC) may be a more accurate measure of body iron stores.