Infectious Disease Sensitivity to Climate and Other Driver‐Pressure Changes: Research Effort and Gaps for Lyme Disease and Cryptosporidiosis

Abstract

Climate sensitivity of infectious diseases is discussed in many studies. A quantitative basis for distinguishing and predicting the disease impacts of climate and other environmental and anthropogenic driver‐pressure changes, however, is often lacking. To assess research effort and identify possible key gaps that can guide further research, we here apply a scoping review approach to two widespread infectious diseases: Lyme disease (LD) as a vector‐borne and cryptosporidiosis as a water‐borne disease. Based on the emerging publication data, we further structure and quantitatively assess the driver‐pressure foci and interlinkages considered in the published research so far. This shows important research gaps for the roles of rarely investigated water‐related and socioeconomic factors for LD, and land‐related factors for cryptosporidiosis. For both diseases, the interactions of host and parasite communities with climate and other driver‐pressure factors are understudied, as are also important world regions relative to the disease geographies; in particular, Asia and Africa emerge as main geographic gaps for LD and cryptosporidiosis research, respectively. The scoping approach developed and gaps identified in this study should be useful for further assessment and guidance of research on infectious disease sensitivity to climate and other environmental and anthropogenic changes around the world.This study looks at how the effects of changes in climate and other environmental and anthropogenic factors are addressed in research on two widespread infectious diseases: Lyme disease (LD) (tick‐borne) and cryptosporidiosis (water‐borne). By a scoping review of existing research publications, the study identifies key gaps that need to be bridged in future research. For LD, more research is needed on water‐related and socioeconomic factors and their climate linkages, while for cryptosporidiosis, land‐related factors and their linkages with climate need further exploration. For both diseases, the interactions between host and parasite communities and their changes along with those in climate and other environmental factors emerge as insufficiently studied. Geographically, research is lacking for LD in Asia and cryptosporidiosis in Africa. By identifying and highlighting these research gaps, this study aims to guide future research on how changes in climate and other factors, and their interlinkages affect these infectious diseases around the world. Studies on Lyme disease (LD) and cryptosporidiosis relationships with climate lack coupling with other environmental and anthropogenic factors Driver‐pressure interactions with host and parasite communities are generally understudied Asia and Africa are main geographic research gaps for LD and cryptosporidiosis research, respectively