This study was undertaken to assess the antibacterial potential of a polyphenolic compound (+)-lariciresinol isolated from Rubia philippinensis against selected foodborne pathogens Staphylococcus aureus KCTC1621 and Escherichia coli O157:H7. (+)-Lariciresinol at the tested concentrations (250 μg/disk) evoked a significant antibacterial effect as a diameter of inhibition zones (12.1-14.9 mm) with minimum inhibitory concentration (MIC), and minimum bactericidal concentration values of 125-250 and 125-250 μg/mL, respectively. Furthermore, (+)-lariciresinol at MIC showed reduction in bacterial cell viabilities, efflux of potassium (K+) ions and release of 260 nm materials against E. coli O157:H7 and S. aureus KCTC1621. Moreover, deteriorated cell wall morphology of E. coli O157:H7 and S. aureus KCTC1621 cells treated with (+)-lariciresinol at MIC further confirmed its inhibitory effect against the tested pathogens, suggesting it to be an alternative means of antimicrobials.
CITATION STYLE
Bajpai, V. K., Shukla, S., Paek, W. K., Lim, J., Kumar, P., Kumar, P., & Na, M. K. (2017). Efficacy of (+)-lariciresinol to control bacterial growth of Staphylococcus aureus and Escherichia coli O157:H7. Frontiers in Microbiology, 8(MAY). https://doi.org/10.3389/fmicb.2017.00804
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