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In vitro activity of ciprofloxacin, sparfloxacin, ofloxacin, amikacin and rifampicin against Ghanaian isolates of Mycobacterium ulcerans

Journal of Antimicrobial Chemotherapy (2000) 45(2) 231-233
DOI: 10.1093/jac/45.2.231
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Abstract

MICs of ciprofloxacin, sparfloxacin, ofloxacin, amikacin and rifampicin were determined for 14 primary clinical isolates and three reference isolates of Mycobacterium ulcerans by modifying a standard agar dilution method for testing Mycobacterium tuberculosis sensitivity. All these antimicrobials were active against every isolate of M. ulcerans. Sparfloxacin exhibited the highest activity and ofloxacin was the least effective. Rifampicin exhibited the broadest range of activity.

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Thangaraj, H. S., Adjei, O., Allen, B. W., Portaels, F., Evans, M. R. W., Banerjee, D. K., & Wansbrough-Jones, M. H. (2000). In vitro activity of ciprofloxacin, sparfloxacin, ofloxacin, amikacin and rifampicin against Ghanaian isolates of Mycobacterium ulcerans. Journal of Antimicrobial Chemotherapy, 45(2), 231–233. https://doi.org/10.1093/jac/45.2.231

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