Associação entre uso de álcool em indivíduos com AIDS e adesão ao tratamento antirretroviral: Uma revisão da literatura

Abstract

Objective: The purpose of this work was to make a systematic review of the literature, using the MedLine data basis, about the alcohol usage/abuse/ dependence as a risk factor to the adherence reduction, the viral load reduction or even a worse clinical outcome in HIV patients in the usage of highly active antiretroviral therapy (HAART). Method: It was made a systematic research in the MedLine data basis using the words: "HAART", "adherence" and "alcohol" with the purpose of finding articles about the themes: evaluations or association between the alcohol usage/abuse/dependence and adherence/suppression of the viral load/clinical outcome in HIV patients in the usage of antiretroviral therapy. Results: The search found 65 articles. However, only 21 of this achieved the pre-established criteria and have been selected. It was found a positive association among the usage/abuse/dependence of the alcohol and the low adherence/low viral load suppression/worse clinical outcome in 18 (85,7%) of the articles. Conclusion: We could conclude that the alcohol usage/ abuse/dependence is a risk factor to the low adherence/low viral load suppression/worse clinical outcome in HIV patients in the usage of HAART.