Mapping brains on grids of features for schizophrenia analysis

Abstract

This paper exploits the embedding provided by the counting grid model and proposes a framework for the classification and the analysis of brain MRI images. Each brain, encoded by a count of local features, is mapped into a window on a grid of feature distributions. Similar sample are mapped in close proximity on the grid and their commonalities in their feature distributions are reflected in the overlap of windows on the grid. Here we exploited these properties to design a novel kernel and a visualization strategy which we applied to the analysis of schizophrenic patients. Experiments report a clear improvement in classification accuracy as compared with similar methods. Moreover, our visualizations are able to highlight brain clusters and to obtain a visual interpretation of the features related to the disease. © 2014 Springer International Publishing.