A mild, efficient and improved protocol for the Friedländer synthesis of quinolines using Lewis acidic ionic liquid

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Abstract

Lewis acidic ionic liquid is shown to be for the first time an excellent medium and efficient catalyst for the synthesis of quinolines at room temperature from o-amino aromatic carbonyls and ketones containing active methylene group.

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Karthikeyan, G., & Perumal, P. T. (2004). A mild, efficient and improved protocol for the Friedländer synthesis of quinolines using Lewis acidic ionic liquid. Journal of Heterocyclic Chemistry, 41(6), 1039–1041. https://doi.org/10.1002/jhet.5570410632

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