A rigorous derivation of the chemical master equation

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Abstract

It is widely believed that the chemical master equation has no rigorous microphysical basis, and hence no a priori claim to validity. This view is challenged here through arguments purporting to show that the chemical master equation is exact for any gas-phase chemical system that is kept well stirred and thermally equilibrated. © 1992.

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Gillespie, D. T. (1992). A rigorous derivation of the chemical master equation. Physica A: Statistical Mechanics and Its Applications, 188(1–3), 404–425. https://doi.org/10.1016/0378-4371(92)90283-V

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