The aire family expands

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Abstract

T cell tolerance depends upon Aire-expressing cells to purge the T cell repertoire of autoreactive clones. Once thought to be the exclusive domain of thymic epithelial cells, a new study by Yamano et al. (https://doi.org/10.1084/jem.20181430) in this issue of JEM identifies ILC3-like cells in the lymph nodes with similar properties.

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APA

Liston, A., & Dooley, J. (2019). The aire family expands. Journal of Experimental Medicine, 216(5), 1010–1011. https://doi.org/10.1084/jem.20190246

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