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Thionation of bicyclic β-lactam compounds by Lawesson's reagent

Arkivoc (2005) 2005(12) 282-294
DOI: 10.3998/ark.5550190.0006.c22
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Abstract

We have developed a study on the thionation of cephalosporins and penicillins using Lawesson's reagent. Best results were obtained in the preparation of 7α-methoxy-8-thioxocephalosporins (70-98% isolated yield), and 6α-methoxy-7-thioxopenicillins (14% isolated yield). © ARKAT.

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Poeylaut Palena, A. A., & Mata, E. G. (2005). Thionation of bicyclic β-lactam compounds by Lawesson’s reagent. Arkivoc, 2005(12), 282–294. https://doi.org/10.3998/ark.5550190.0006.c22

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